In 2017, she became a Broad Institute Scientist. Her first NIH R01 grant was awarded in 2010, at the age of 33, far earlier than the average. In January 2007, Carpenter founded her laboratory at the Broad Institute of Harvard and MIT, as the Director of the Imaging Platform. Using this new tool, she led a team of 5 researchers to develop advanced data mining methods to systematically examine the necessity of proteins for a variety of biological processes. This required new image analysis methods, so Carpenter and collaborator Thouis Jones designed and in 2005 released the first open-source high-throughput cell image analysis software, CellProfiler, which was first published in 2006. Her research focused on high-throughput microscopy and living cell microarrays to reveal gene function. Through co-mentoring by Polina Golland, professor at MIT Computer Science and Artificial Intelligence Laboratory, Carpenter transitioned into a computational researcher during this time. Sabatini at the Whitehead Institute for Biomedical Research, Cambridge MA, during her postdoctoral work (July 2003 to December 2006).
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Post-doctoral training and creation of CellProfiler software Ĭarpenter trained in the laboratory of David M. She received her PhD in cell biology in May 2003. This work laid the foundation for studies of engineered regions of the genome, the movement of genes within the nucleus upon gene activation, and chromatin-related high-throughput screens. There, she developed molecular biology and automated imaging systems to rapidly assess the effects of transcriptional activators on large-scale chromatin structure using fluorescence microscopy. Belmont at the University of Illinois, Urbana-Champaign. Doe, then at the University of Illinois, Urbana-Champaign.Ĭarpenter carried out research for her Ph.D. Following her graduation, she spent a summer working on enhancers in Drosophila neural development as a research assistant in the laboratory of Chris Q.
Malone at the University of Iowa, working on the control of recombination in yeast. During this time, she spent a summer in 1996 as an HHMI Undergraduate Research Fellow in the laboratory of Robert E. in Biological Sciences in 1997 from Purdue University, West Lafayette.
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